Beyond the wound：why diabetic foot is the“tip of the iceberg”of systemic disease

DAI Linlin，HAN Junfeng

Abstract: Diabetic foot ulcer（DFU）has traditionally been regarded as a localized wound problem，but emerging evidence indicates that it is essentially a focal manifestation of systemic metabolic-inflammatory-immune decompensation.  ......

Chin J Clin Res,2026,39(6): 815-819.   [PDF]

• Diagnosis and treatment of diabetic cardiovascular autonomic neuropathy with Chinese medicine and Western medicine

  ZHAO Siwen，BI Yan，WANG Weimin，WU Jiulong，FANG Qijun，LI Chenxi

  Chin J Clin Res,2026,39(6):820-823,828. [PDF]

• Role and mechanisms of glucagon⁃like peptide⁃1 receptor agonists in the treatment of diabetes⁃associated cognitive dysfunction

  LI Hongju，XUE Jun

  Chin J Clin Res,2026,39(6):824-828. [PDF]

  
  

• Gut microbiota and diabetic gastrointestinal autonomic neuropath

  CHEN Nuo，ZHANGQing，LIU Juan，YUAN Xiaoqing，YE Xinhua

  Chin J Clin Res,2026,39(6):829-833. [PDF]

• A prospective cohort study on Qiling Hushen Formula in the treatment of type 2 diabetic kidney disease 

  ZHANG Mingjin，WANG Shuqi，SHENG Pei，AN Xiaofei

  Chin J Clin Res,2026,39(6):834-840. [PDF]

• Short-term continuous subcutaneous insulin infusion combined with metformin and semaglutide in the 

  treatment of type 2 diabetes mellitus 

  ZHANG Mimi，LUHuaxuan，TANG Wei 

  Chin J Clin Res,2026,39(6):841-845,851.  [PDF]

• Correlation of plasma mitochondrial DNA，sTREM⁃1 levels with the severity of infection and inflammatory

  state in diabetic foot ulcers 

  HU Junsheng，HUANG Rong，HUANG Yi，LI Mengfan，ZENG Guang，JIN Yongzhi 

  Chin J Clin Res,2026,39(6):846-851. [PDF]

  
  

• Effect of semaglutide combined with metformin on type 2 diabetes mellitus and its regulation of

  IL⁃6/JAK2/STAT3 signaling axis    

  LI Xiaoxia，LIU Hao，YAO Chaoran 

  Chin J Clin Res,2026,39(6):852-856.  [PDF]

  
  

• Association between heart rate variability and apolipoprotein B/ apolipoprotein A1 ratio in patients with 

  diabetic kidney disease stratified by estimated glomerular filtration rate   

  YAN Wenyan，YANGJuan，BAI Mingchuan，JIANG Luyu

  Chin J Clin Res,2026,39(6):857-862,867.  [PDF]

• Diagnostic value of serum LRG1 and SFRP4 levels for early renal injury in patients with gestational  

  diabetes mellitus    

  LYU Xiaojuan，LONG Xiaoyu，XIE Xiufeng

  Chin J Clin Res,2026,39(6):863-867. [PDF]

• Relationship of serum miR⁃93⁃5p and miR⁃124⁃3p levels with short⁃ term progression of albuminuria and  

  prognosis in patients with diabetic nephropathy 

  CAO Dan，ZHANG Guihong 

  Chin J Clin Res,2026,39(6):868-872.  [PDF]

  
  

• Data mining on the medication rules of Chinese medicine for diabetic nephropathy   

  ZOU Xunxia，SUN Lili，SU Hao，LUO Mengxing，WANG Kaishuang 

  Chin J Clin Res,2026,39(6):873-878.  [PDF]